Effect of Structured, Moderate Exercise on Kidney Function Decline in Sedentary Older Adults: An Ancillary Analysis of the LIFE Study Randomized Clinical Trial. Results. We examined 4 different methods of estimating the effect of health care on health outcomes.METHODS: We reviewed the contributions of medical care to health outcomes using 4 methods: (1) analyses by McGinnis and Schroeder, (2) Wennberg and colleagues' studies of small area variation, (3) Park and colleagues' analysis of County Health Rankings and Roadmaps, and (4) the RAND Health Insurance Experiment.RESULTS: The 4 methods, using different data sets, produced estimates ranging from 0% to 17% of premature mortality attributable to deficiencies in health care access or delivery. Covid-19 pandemic lessons: uncritical communication of test results can induce more harm than benefit and raises questions on standardized quality criteria for communication and liability. The goal of TRICARE's move toward value-based care is to leverage its size and focus on prevention of disease and injury to maintain the readiness of the U.S. Armed Forces in addition to delivering great outcomes and value to the DoD's nearly 10 million beneficiaries. These assessments were used to compare a physical activity intervention with a health education control. We examined the hypothesis that physical activity will have favorable effects on measures of self-efficacy for a 400-m walk and satisfaction with physical functioning in older adults 70+ years of age who have deficits in mobility. Comparison of Rating Scale, Time Tradeoff, and Conjoint Analysis Methods for Assessment of Preferences in Prostate Cancer. Porzsolt, F., Pfuhl, G., Kaplan, R. M., Eisemann, M. The terminology conflict on efficacy and effectiveness in healthcare. Thus, ACE I/D genotype appears to play a role in modulating functional responses to exercise training in seniors. View details for DOI 10.1001/jama.2014.5616, View details for Web of Science ID 000337301500019. Symptoms of lack of positive affect decreased more in men compared to women, particularly in those possessing the 5-HTT L allele, but the effect did not differ by intervention arm. A., Gill, T. M., Marsh, A. P., Hsu, F., Yaghjyan, L., Woods, A. J., Glynn, N. W., King, A. C., Newton, R. L., Fielding, R. A., Pahor, M., Manini, T. M., Lifestyles Intervention and Independence for Elders Study Investigators. Results of prior research have been mixed, including findings of a 3:1 incidence ratio for males vs. females, but increasing AS rates among females.METHODS: We estimated the incidence of AS in a retrospective cohort study of diverse, working-age US military service members during March 2014 - June 2017 (N = 728,556) who underwent clinical practice guideline-directed screening for chronic back pain. B., Lifestyle Interventions and Independence for Elders Study Group, Pahor, M., Guralnik, J. M., Anton, S. D., Buford, T. W., Leeuwenburgh, C., Nayfield, S. G., Manini, T. M., Caudle, C., Crump, L., Holmes, L., Lee, J., Lu, C., Miller, M. E., Espeland, M. A., Ambrosius, W. T., Applegate, W., Beavers, D. P., Byington, R. P., Cook, D., Furberg, C. D., Harvin, L. N., Henkin, L., Hepler, J., Hsu, F., Joyce, K., Lovato, L., Pierce, J., Roberson, W., Robertson, J., Rushing, J., Rushing, S., Stowe, C. L., Walkup, M. P., Hire, D., Rejeski, W. J., Katula, J. Older people who lose mobility are less likely to remain in the community; demonstrate higher rates of morbidity, mortality, and hospitalizations; and experience a poorer quality of life. Incidence of Ankylosing Spondylitis Among Male and Female United States Army Personnel. Dismiss. A serious adverse reaction rate of 1/100,000 was more likely to discourage vaccine use in comparison to rates of 1/million or 1/100 million. Porzsolt, F., Wiedemann, F., Phlippen, M., Weiss, C., Weiss, M., Schmaling, K., Kaplan, R. M. Efficacy and effectiveness studies of depression are not well-differentiated in the literature: a systematic review. However, further study is needed to definitively determine the utility of CAF as a biomarker of physical function. To advance the field, we need a greater emphasis on evaluations that ask 'Does the treatment work under real-world conditions? Genealogy for Robert Roman Kaplan (1908 - 1978) family tree on Geni, with over 240 million profiles of ancestors and living relatives. Groessl, E. J., Kaplan, R. M., Rejeski, W., Katula, J. In this special section, we acknowledge a wide range of variability in terms of behavioral interventions typically delivered in nonclinical versus more traditional clinical settings. These mixed results might reflect heterogeneity in response to physical activity, with some subgroups of individuals responding positively, but not others.1) To examine the impact of genetic variation and sex on changes in depressive symptoms in older adults after a physical activity (PA) intervention, and 2) to determine if PA differentially improves particular symptom dimensions of depression.Randomized controlled trial.Four field centers (Cooper Institute, Stanford University, University of Pittsburgh, and Wake Forest University).396 community-dwelling adults aged 70-89 years who participated in the Lifestyle Interventions and Independence for Elders Pilot Study (LIFE-P).12-month PA intervention compared to an education control.Polymorphisms in the serotonin transporter (5-HTT), brain-derived neurotrophic factor (BDNF), and apolipoprotein E (APOE) genes; 12-month change in the Center for Epidemiologic Studies Depression Scale total score, as well as scores on the depressed affect, somatic symptoms, and lack of positive affect subscales.Men randomized to the PA arm showed the greatest decreases in somatic symptoms, with a preferential benefit in male carriers of the BDNF Met allele. Estimates of the effect of behavioral factors ranged from 16% to 65%.CONCLUSIONS: The results converge to suggest that restricted access to medical care accounts for about 10% of premature death or other undesirable health outcomes. American science produces the bestand most expensivemedical treatments in the world. These null results were accompanied by suggestive evidence that the physical activity program may reduce the rate of fall related fractures and hospital admissions in men.Trial registration ClinicalsTrials.gov NCT01072500. Physical activity was measured by step count and minutes of moderate-intensity activity using accelerometers.Main Outcomes and Measures: The primary outcome was change in eGFRCysC. Published by Wadsworth Publishing, 2000. Of the 173 total ClinicalTrials.gov records identified across the five projects, between 11 and 43% did not have an associated publication. Mendel Kaplan, a prominent leader of the South African Jewish community, died in South Africa on Thursday evening at the age of 73 after suffering a massive stroke on Tuesday. All titles by Robert M. Kaplan: Handbook of Health Psychology and Behavioral Medicine Edited by Jerry M. Suls, Karina W. Davidson, and Robert M. Kaplan Hardcover B., Sink, K., Gill, T. M., King, A. C., Miller, M. E., Guralnik, J., Katula, J., Church, T., Manini, T., Reid, K. F., McDermott, M. M. The MAT-sf: Identifying Risk for Major Mobility Disability. Work Experience T2 Hospitality 1996- Education Bachelor of Science - Physics Stony Brook University Doctor of Jurisprudence Accelerometer patterns were characterized as bouts of sedentary (<100 counts/min; 1, 10, 30, 60 minute lengths) and activity (100 counts/min; 1, 2, 5, 10 minute lengths) time. View details for Web of Science ID 000282842100012, View details for PubMedCentralID PMC3091594. Economic arguments supporting modern NEMT are important given decreased support for human services spending. These differing services compete for the same resources and it is difficult to compare their value. Foreign Correspondent. Robert M. Kaplan is a Distinguished Research Professor of Health Policy and Management in the Fielding School. Free delivery worldwide on over 20 million titles. Developed under the prevailing zeitgeist of the biomedical model, behavioral and social science has often been underfunded at NIH. The average cost/participant was $1134 and $175 for the PA and the comparison interventions, respectively. Hierarchical linear regression models were used to examine correlates of HRQOL.The mean QWB-SA score for the sample was 0.630 on an interval scale ranging from 0.0 (death) to 1.0 (asymptomatic, optimal functioning). The mean DSC task scores were 46.26 points for the physical activity group vs 46.28 for the health education group (mean difference, -0.01 points [95% CI, -0.80 to 0.77 points], P=.97). Data are sparse regarding the impacts of habitual physical activity (PA) and sedentary behavior on cardiovascular (CV) risk in older adults with mobility limitations.This study examined the baseline, cross-sectional association between CV risk and objectively measured PA among participants in the Lifestyle Interventions and Independence for Elders (LIFE) study. The Pittsburgh Fatigability Scale measured physical and mental fatigability (score 0-50; higher physical fatigability15; higher mental fatigability13). Cape Town, South Africa . Dr Robert M Kaplan Profile and History . Partitioning the MAT-sf into four groups revealed that persons with scores <40, 40-49, 50-59, and 60+ had failure rates across 42 months of follow-up of 66%, 52%, 35%, and 22%, respectively.The MAT-sf is a quick and efficient way of identifying older adults at risk for MMD. Acceptable levels of data completeness (>83%) were achieved on all computer-based measures; however, rates of missing data were higher among older participants (odds ratio = 1.06 for each additional year; p < 0.001) and those who reported no current computer use (odds ratio = 2.71; p < 0.001). Espeland, M. A., Katula, J. View details for DOI 10.1176/appi.ps.201900098. It employs 11-20 people and has $1M-$5M of revenue. The ability of our field to communicate cost-effectiveness data to policy makers, employers, and insurers that incorporates implementation costs is central to the likelihood of our interventions being adopted by practitioners and reimbursed by payers. With more than 550 articles, chapters, and books, Dr. Kaplan is one of the most cited authors in his field. Botoseneanu, A., Ambrosius, W. T., Beavers, D. P., De Rekeneire, N., Anton, S., Church, T., Folta, S. C., Goodpaster, B. H., King, A. C., Nicklas, B. J., Spring, B., Wang, X., Gill, T. M. Combined Reduced Forced Expiratory Volume in 1 Second (FEV1) and Peripheral Artery Disease in Sedentary Elders With Functional Limitations. When expanded it provides a list of search options that will switch the search inputs to match the current selection. We used an exploratory alpha level of p, View details for DOI 10.1016/j.exger.2018.12.003, View details for Web of Science ID 000455223100016, View details for PubMedCentralID PMC6331252. Parasympathetic activity indexed by skin conductance response and high-frequency heart rate variability also showed more favorable outcomes in the IBMT group. Across 2 years, changes in ABI were not associated with changes in cognitive function.In an older cohort sedentary individuals with dementia and with functional limitations, lower baseline ABI was independently correlated with cognitive function and associated with greater 2-year risk for progression to mild cognitive impairment or probable dementia. Robert A Kaplan, age 70. Linking among different measures and consensus on standard HRQoL measurement should now be prioritized. OBJECTIVES: To evaluate the effect of hospitalizations on patterns of sedentary and physical activity time in mobility-limited older adults randomized to structured physical activity or health education.DESIGN: Secondary analysis of investigator-blinded, parallel-group, randomized trial conducted at 8 U.S. centers between February 2010 and December 2013.PARTICIPANTS: Sedentary men and women aged 70 to 89 at baseline who wore a hip-fitted accelerometer 7 consecutive days at baseline and 6, 12, and 24 months after randomization (N=1,341).MEASUREMENTS: Participants were randomized to a physical activity (PA; n = 669) intervention that included aerobic, resistance, and flexibility training or to a health education (HE; n = 672) intervention that consisted of workshops on older adult health and light upper-extremity stretching. Student Workbook for Kaplan/Saccuzzos Psychological Testing: Principles, Applications, and Issues, 7th by Robert M. Kaplan , Dennis P. Saccuzzo ISBN 9780495597742 (978--495-59774-2) Another 15% . View details for DOI 10.1161/JAHA.114.001288. View details for Web of Science ID 000349893300002, View details for PubMedCentralID PMC4333053, Because they are potentially modifiable and may coexist, we evaluated the combined occurrence of a reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease (PAD), including its association with exertional symptoms, physical inactivity, and impaired mobility, in sedentary elders with functional limitations.Cross sectional.Lifestyle Interventions and Independence in Elder (LIFE) Study.A total of 1307 sedentary community-dwelling persons, mean age 78.9, with functional limitations (Short Physical Performance Battery [SPPB] <10).A reduced FEV1 was defined by a z-score less than -1.64 ( My wife, Jackie, and I were briefly in South Africa just last month, mainly to visit my 98-year-old mother who is barely hanging on in Knysna. The mean HVLT-R delayed recall scores were 7.22 for the physical activity group vs 7.25 for the health education group (mean difference, -0.03 words [95% CI, -0.29 to 0.24 words], P=.84). Lower mental health functioning also had a significant impact on cost. View details for DOI 10.14283/jfa.2016.76, View details for Web of Science ID 000449826700002, View details for PubMedCentralID PMC4905714. Although contributions of different risk factors varied slightly by race/ethnicity, most findings were similar across groups, and women who had both a healthy weight and were in the highest tertile of physical activity had less than one-third the risk of diabetes compared with obese and inactive women.Despite large racial/ethnic differences in diabetes incidence, most variability could be attributed to lifestyle factors. Also, a sizable subgroup required one or more rest stops. We here illustrate a quantification of the difference between objective and subjective risks.The objective risks (or chances) can be obtained from traditional 22 tables by calculating the positive (+LR) and negative (-LR) likelihood ratios. We randomized a volunteer sample of 1635 sedentary men and women aged 70 to 89 years who had physical limitations, defined as a score on the Short Physical Performance Battery of 9 or below, but were able to walk 400 m.Participants were randomized to a structured, moderate-intensity physical activity program (n=818) conducted in a center (twice/wk) and at home (3-4 times/wk) that included aerobic, resistance, and flexibility training activities or to a health education program (n=817) consisting of workshops on topics relevant to older adults and upper extremity stretching exercises.The primary outcome was major mobility disability objectively defined by loss of ability to walk 400 m.Incident major mobility disability occurred in 30.1% (246 participants) of the physical activity group and 35.5% (290 participants) of the health education group (hazard ratio [HR], 0.82 [95% CI, 0.69-0.98], P=.03).Persistent mobility disability was experienced by 120 participants (14.7%) in the physical activity group and 162 participants (19.8%) in the health education group (HR, 0.72 [95% CI, 0.57-0.91]; P=.006). This multisite RCT compared physical activity to health education among 1,635 randomly assigned sedentary older adults at risk for mobility disability in 2010-2011. View details for DOI 10.1136/bmjebm-2020-111641. Those with less education were also more likely to be uninsured throughout the year. He is currently Editor-in-Chief of Health Psychology and is the former Editor-in-Chief of the Annals of Behavioral Medicine. Methods. Converging evidence suggests that physical activity is an effective intervention for both clinical depression and sub-threshold depressive symptoms; however, findings are not always consistent. Dr. Kaplan is expected to join the NIH in early 2011. We defined incident MMD as the inability to walk 400-m at follow-up visits; PMMD was defined as two consecutive walk failures. A consequence of neglecting to employ standardized cost-effectiveness analysis is that behavioral, psychological, and environmental interventions may be left out of resource allocation discussions. B., Tudor-Locke, C., Gill, T. M. Light Intensity Physical Activity and Sedentary Behavior in Relation to Body Mass Index and Grip Strength in Older Adults: Cross-Sectional Findings from the Lifestyle Interventions and Independence for Elders (LIFE) Study. The mental component summary (MCS) score of the 12-item Short Form (SF-12) was used as a measure of mental health status. Robert D. Kaplan, The Return of Marco Polo's World: War, Strategy, and American Interests in the Twenty-first Century 2 likes Like "Today, despite the jet and information age, 90 percent of global commerce and two thirds of all petroleum supplies travel by sea." Robert D. Kaplan, Monsoon: The Indian Ocean and the Future of American Power The company is headquartered in Wollongong, New South Wales, Australia. Rejeski, W. J., King, A. C., Katula, J. Interview: Robert Kaplan, . Robert D. Kaplan - Career Reflections Author. PA participants accrued 0.047 per person more Quality-Adjusted Life-Years (QALYs) than health education participants. Cost analyses were conducted from the "payer's" perspective, with a 1-year time horizon. However, formal medical care is one of many alternatives for improving health. We estimate the impact on U.S. health care spending if individuals with uncomplicated, acute alcohol intoxication were treated in sobering centers instead of the emergency department. Application of standardized methods of cost-effectiveness analysis will allow direct comparisons between investing in behavioral interventions programs in comparison to a wide range of other alternatives. This button displays the currently selected search type. Using hospital discharge data for the period 2007-16, we compared acute myocardial infarction (AMI) hospitalization rates in San Diego County and the rest of the state before and after the demonstration project started. Rapid eGFRCysC decline was defined by the high tertile threshold of 6.7%/y.Results: Among the 1199 participants in the analysis, the mean (SD) age was 78.9 (5.2) years, and 800 (66.7%) were women. Longitudinal studies are needed to investigate whether MetS accelerates declines in functional status in high-risk older adults and to inform clinical and public health interventions aimed at preventing or delaying disability in this group. The group training benefit was reduced to 23% (hazard ratio=0.77; 95% confidence interval: 0.56-1.07, P=.11) in the multivariate-adjusted model.Findings suggest that adding group training to individual therapy may be associated with reduction in the composite end point. Competing interests: None declared Competing interests: No competing interests 20 February 2004 Robert M Kaplan psychiatrist 2500 Exercise improved gait speed by 0.06 0.01 m/sec and SPPB score by 0.72 0.16 points among those with at least one D allele (ID/DD carriers), but function was not improved among II carriers. Prevalence rates were 33.0% for insomnia, 18.1% for daytime drowsiness, 47.8% for poor sleep quality, and 32.9% for high risk of sleep apnea. When expanded it provides a list of search options that will switch the search inputs to match the current selection. In 2011 a multistakeholder population health collaborative consisting of partners at the federal, state, and local levels launched Be There San Diego. View details for Web of Science ID 000341167700011 This study aimed to evaluate the association of ACE I/D genotypes with changes in physical function among Caucasian older adults (n = 283) following 12 mo of either structured, multimodal physical activity or health education. A., Pahor, M. Performance of a computer-based assessment of cognitive function measures in two cohorts of seniors. We compared two groups of older adults with 10 years of mindfulness meditation (integrative body-mind training, IBMT) or physical exercise (PE) experience to demonstrate their effects on brain, physiology and behavior. Forensic psychiatrist and historian Robert M. Kaplan is of the opinion the coronavirus pandemic will not last that much longer. See all books authored by Robert M. Kaplan, including Psychological Testing: Principles, Applications, and Issues, and More Than Medicine: The Case for Social Investment to Improve America's Health, and more on ThriftBooks.com. Participants with insomnia had a mean ISI score of 12.1, those with daytime drowsiness had a mean ESS score of 12.5, and those with poor sleep quality had a mean PSQI score of 9.2. A., Bailey, C., Charpentier, P., Hawthorne-Jones, G., Mignosa, B., Lewis, L., Williamson, J., Hendrie, H. C., Rapp, S. R., Verghese, J., Woolard, N., Espeland, M., Jennings, J., Wilson, V. K., Pepine, C. J., Ariet, M., Handberg, E., Deluca, D., Hill, J., Szady, A., Chupp, G. L., Flynn, G. M., Hankinson, J. L., Fragoso, C., Groessl, E. J., Kaplan, R. M., LIFE Study Grp. Click a location below to find Robert more easily. Scheuter, C., Rochlin, D. H., Lee, C., Milstein, A., Kaplan, R. M. Contributions of Health Care to Longevity: A Review of 4 Estimation Methods. America's medical system is . Wanigatunga, A. Basal sIgA level was significantly higher and cortisol concentration was lower in the IBMT group. All cognitive measures loaded onto the first principal component (global cognitive function), which accounted for 40% of the overall variance.Our results support the use of computer-based tools for assessing cognitive function in multicenter clinical trials of older individuals. These results are consistent with the hypothesis that replacing sedentary activities with light intensity activities could lead to lower BMI levels and obesity prevalence among the population of older adults. Prof. Robert Kaplan is the Baker Foundation Professor at Harvard Business School. Fields of study that have received more extramural funding are associated with greater growth in faculty and higher faculty salaries. Robert M Kaplan South African Journal of Psychiatry | Vol 9, No 2 | a137 | DOI: https://doi.org/10.4102/sajpsychiatry.v9i2.137 | 2003 Robert M Kaplan | This work is licensed under CC Attribution 4.0 Submitted: 11 August 2008 | Published: 01 September 2003 About the author (s) Robert M Kaplan, HMPG, South Africa The time spent engaging in activities 100 to 499 as well as 500 counts/min was associated with decreased risk among both those with and without CVD (P<0.05). Robert Q. v Dembek M. je sasou turnaja South Africa F3, Singles. The physical activity and exercise intervention resulted in statistically significantly lower decline in eGFRCysC over 2 years compared with the health education arm (mean difference, 0.96 mL/min/1.73 m2; 95% CI, 0.02-1.91 mL/min/1.73 m2) and lower odds of rapid eGFRCysC decline (odds ratio, 0.79; 95% CI, 0.65-0.97).Conclusions and Relevance: Results of this ancillary analysis of a randomized clinical trial showed that when compared with health education, a physical activity and exercise intervention slowed the rate of decline in eGFRCysC among community-dwelling sedentary older adults. In the Monte Carlo modeling, we found annual national savings of $99.02 million (95% CI: $95.89-$102.19 million), $792.34 million (95% CI: $767.09-$817.58 million), and $1,185.51 million (95% CI: $1,150.64-$1,226.37 million) with diversion rates of 5%, 40%, and 60%, respectively. Patterns of federal funding for research may have a significant influence on scientific disciplines. Robert M. Kaplan, Michael L. Spittel, and Tia L. Zeno Volume 1, Issue 1 https://doi.org/10.1177/2372732214549754 Abstract Tweet Key Points Introduction U.S. Life Expectancy in International Perspective Explanations of the Relationship Between Education and Life Expectancy Relationship Between Education and Changes in Life Expectancy Conclusions The Isaac and Jessie Kaplan Centre for Jewish Studies and Research, . The outcome of interest was the first occurrence of MMD or incident MMD.After controlling for age, sex, clinic site, and treatment arm, baseline MAT-sf scores were found to be effective in identifying risk for MMD (p < .0001). OBJECTIVES: Our aim was to examine the impacts of baseline fatigue on the effectiveness of a physical activity (PA) intervention to prevent major mobility disability (MMD) and persistent major mobility disability (PMMD) in participants from the Lifestyle Interventions and Independence for Elders (LIFE) study.DESIGN: Prospective cohort of individuals aged 65years or older undergoing structured PA intervention or health education (HE) for a mean of 2.6years.SETTING: LIFE was a multicenter eight-site randomized trial that compared the efficacy of a structured PA intervention with an HE program in reducing the incidence of MMD.PARTICIPANTS: Study participants (N=1591) at baseline were 78.95.2years of age, with low PA and at risk for mobility impairment.MEASUREMENTS: Self-reported fatigue was assessed using the modified trait version of the Exercise-Induced Feelings Inventory, a six-question scale rating energy levels in the past week. The role of economic analyses in promoting adoption of behavioral and psychosocial interventions in clinical settings. Outcome estimates were determined at year 2, accounting for implementation and steady-state intervention costs.RESULTS: After accounting for implementation and recurring operating costs of approximately $9.5 billion, estimated net cost savings of between $13 and $41 billion can be accomplished concurrently with improvements in quality and experience of coordinated chronic care ($0.01-$6.8 billion), cognitively protective acute care ($8.7-$26.6 billion), timely caregiver support ($4.3-$7.5 billion), and caregiver efficiency ($4.1-$7.2 billion).CONCLUSION: A high-value care model for AD may improve the experience of patients with AD while significantly lowering costs. A., Brubaker, P. H., Mihalko, S. L., Jennings, J. M., Hadley, E. C., Romashkan, S., Patel, K., Bonds, D., McDermott, M. M., Spring, B., Hauser, J., Kerwin, D., Domanchuk, K., Graff, R., Rego, A., Church, T. S., Blair, S. N., Myers, V. H., Monce, R., Britt, N. E., Harris, M., McGucken, A., Rodarte, R., Millet, H. K., Tudor-Locke, C., Butitta, B. P., Donatto, S. G., Cocreham, S. H., Castro, C. M., Haskell, W. L., Stafford, R. S., Pruitt, L. A., Yank, V., Berra, K., Bell, C., Thiessen, R. M., Youngman, K. P., Virgen, S. B., Maldonado, E., Tarin, K. N., Klaftenegger, H., Prosak, C. A., Campero, I., Garcia, D. M., Soto, J., Chio, L., Hoskins, D., Nelson, M. E., Folta, S. C., Phillips, E. M., Liu, C. K., McDavitt, E. C., Reid, K. F., Kirn, D. R., Pasha, E. P., Kim, W. S., Krol, J. M., Beard, V. E., Tsiroyannis, E. X., Hau, C., Marsiske, M., Sandesara, B. D., Black, M. L., Burk, W. L., Hoover, B. M., Knaggs, J. D., Marena, W. C., Korytov, I., Curtis, S. D., Lorow, M. S., Goswami, C. S., Lewis, M. A., Kamen, M., Bitz, J. N., Stanton, B. K., Hicks, T. T., Gay, C. W., Xie, C., Morris, H. L., Singletary, F. F., Causer, J., Yonce, S., Radcliff, K. A., Smith, M., Scott, J. S., Rodriguez, M. M., Fitch, M. S., Dunn, M. C., Schllesinger, J. Q., Newman, A. No significant differences were found across dynapenia and obesity status for all other metabolic components (P>.05). Definitive data from large long-term randomized trials are lacking.To determine whether a long-term, structured, moderate-intensity physical activity program is associated with a lower risk for frailty and whether frailty status alters the effect of physical activity on the reduction in major mobility disability (MMD) risk.Multicenter, single-blind, randomized trial.8 centers in the United States.1635 community-dwelling adults, aged 70 to 89 years, with functional limitations.A structured, moderate-intensity physical activity program incorporating aerobic, resistance, and flexibility activities or a health education program consisting of workshops and stretching exercises.Frailty, as defined by the SOF (Study of Osteoporotic Fractures) index, at baseline and 6, 12, and 24 months, and MMD, defined as the inability to walk 400 m, for up to 3.5 years.Over 24 months of follow-up, the risk for frailty (n= 1623) was not statistically significantly different in the physical activity versus the health education group (adjusted prevalence difference, -0.021 [95% CI, -0.049 to 0.007]). Associated persons: . Kaplan, R. M., Johnson, S. B., Kobor, P. C. Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons Secondary Analysis of a Randomized Trial. Run Background Search Optout of Search Copy Link. Robert Kaplan. There was no evidence of better activity recovery after hospitalization. Schaettle, P. R., Kaplan, R. S., Lee, V. S., Parkinson, M. D., Gorman, G. H., Browne, M. Transparency of results reporting for depression treatment studies in ClinicalTrials.gov: a cross-sectional study. For the next TRICARE contracts which will begin in 2023, the DoD asked its health-focused federal advisory committee, the Defense Health Board (DHB), to recommend how best to assess and prioritize leading value-based healthcare initiatives identified from private, public, and employer-based health plans.
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