2021:n385. Feb 2021;257:11-18. doi:10.1016/j.ejogrb.2020.11.068, Prabhu M, Cagino K, Matthews KC, et al. Austin, TX: University of Texas at Austin; 2021. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Suggested citation for this article: . Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Acute covid-19 and multisystem inflammatory syndrome in children. SARS-CoV-2 shedding dynamics across the respiratory tract, sex, and disease severity for adult and pediatric COVID-19. References to non-CDC sites on the Internet are May 2022;28(5):986-989. doi:10.3201/eid2805.220166, Saelee R, Zell E, Murthy BP, et al. People reinfected with omicron variant had fewer symptoms, small CDC . Update on Omicron - World Health Organization Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Feb 2022;10(2):e18. 2022:o110. Feb 9 2021;doi:10.1093/cid/ciab100, Singanayagam A, Patel M, Charlett A, et al. What is the Incubation Period for the Omicron Variant and How Long Are Mar 2 2022;376:e068632. During the Delta-dominant period, the mean incubation period was 3.7 (3.44.0) days, and the median was 3.5 (3.23.8) days. doi:10.1148/radiol.2021204522, Doerschug KC, Schmidt GA. The score is derived from an automated algorithm, and represents a weighted count of the amount of attention Altmetric picked up for a research output. The clinical severity of infection with the Omicron variant will become better understood as additional cases are identified and investigated. European Journal of Pediatrics. COVID-19 signs, symptoms and severity of disease: A clinician guide 2021:2021.02.27.21252169. doi:10.1101/2021.02.27.21252169, Jering KS, Claggett BL, Cunningham JW, et al. Multisystem Inflammatory Syndrome in Children by COVID-19 Vaccination Status of Adolescents in France. According to earlier CDC guidance, COVID symptoms can appear anywhere from two to 14 days after someone is exposed to the virus. Estimated overall mean incubation periods and means within percentiles for Omicron and Delta variants in study of SARS-CoV-2 incubation period during the Omicron BA.5-dominant period in Japan* *Values are mean no. Congestion or runny nose. Assignment of epidemiological lineages in an emerging pandemic using the pangolin tool. Symptoms can change over the course of illness and can progress in severity. MMWR and Morbidity and Mortality Weekly Report are service marks of the U.S. Department of Health and Human Services. MMWR Morb Mortal Wkly Rep. May 7 2021;70(18):674-679. doi:10.15585/mmwr.mm7018e1, Zimmermann P, Pittet LF, Curtis N. The Challenge of Studying Long COVID: An Updated Review. (8) Multiple publications have reported cases of people with abnormalities on chest imaging that are consistent with COVID-19 very early in the course of illness, even before the onset of symptoms or a positive COVID-19 test. There was an unexpected error. The decrease in isolation time was largely to decrease the impact and disruption of infection on day-to-day life and allow people to return to work sooner, Oller said. Accessed December 3, 2021. This conversion might result in character translation or format errors in the HTML version. Cough. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Aug 24 2022;75(1):e1165-e1175. Sep 2021;8(9):ofab428. A negative test result closer to the time of travel enhances reduction in transmission risk during travel (6). Mar 2021;82(3):329-338. doi:10.1016/j.jinf.2021.01.022, Di Fusco M, Lin J, Vaghela S, et al. Pediatr Infect Dis J. Mar 1 2022;41(3):e81-e86. A study of the group released on Tuesday by the Centers for Disease Control and Prevention suggested that Omicron may have a shorter incubation period than previous variants: about 72 hours. May 19 2022;386(20):1899-1909. doi:10.1056/NEJMoa2202826, Zambrano LD, Ellington S, Strid P, et al. Lancet Respir Med. In part, I think [the incubation period] strongly depends upon the infected human.. Updated Jan. 27, 2023 The omicron subvariant of COVID-19, BA.5, became one of the dominant strains of the virus in the fall of 2022 in the U.S. At that time, it was the most easily spread strain to date and is able to evade immunity from COVID infection and vaccination. (15) Images of cutaneous findings in COVID-19 are available from the American Academy of Dermatology. This interagency group focuses on the rapid characterization of emerging variants and actively monitors their potential impact on critical SARS-CoV-2 countermeasures, including vaccines, therapeutics, and diagnostics. Here's how Omicron differs from previous variants | Fortune provided as a service to MMWR readers and do not constitute or imply Int J Infect Dis. 2020/08/01/ 2020;81(2):266-275. doi:https://doi.org/10.1016/j.jinf.2020.05.046, Gerver SM, Guy R, Wilson K, et al. Apr 2022;21(4):435-451. doi:10.1080/14760584.2022.2035222, Lee A, Wong SY, Chai LYA, et al. Weekly / December 17, 2021 / 70(50);1731-1734. SARS-CoV-2 Incubation Period during the Omicron BA.5-Dominant Period in Reducing travel-related SARS-CoV-2 transmission with layered mitigation measures: symptom monitoring, quarantine, and testing. Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged >/=65 Years - United States, January-March 2021. No potential conflicts of interest were disclosed. The 95th percentile distribution for incubation period among patients during the BA.5dominant period appeared shorter than that during the BA.1dominant period, although the difference was not statistically significant. Pediatr Infect Dis J. Dec 1 2021;40(12):e482-e487. Clin Infect Dis. Investigation of a SARS-CoV-2 B.1.1.529 (Omicron) Variant Cluster Omicron seems to have a shorter incubation period compared with other variants; the CDC reports that symptoms show up about three days after transmission. Centers for Disease Control and Prevention. Am J Obstet Gynecol MFM. *** To date, at least one confirmed case attributed to the Omicron variant has been identified in the United States through these aircraft contact investigation efforts. 2021/11/01/ 2021;27(11):1658-1665. doi:https://doi.org/10.1016/j.cmi.2021.05.040, Chandler CM, Reid MC, Cherian S, Sabath DE, Edlefsen KL. Cookies used to make website functionality more relevant to you. The rapid antigen test may help gauge infectiousness: If a person tests positive, they should consider themselves contagious, he added. This policy was intended to reduce overall travel volume from the region where Omicron was first identified to delay the introduction and spread of Omicron while U.S. public health measures were enhanced. May 2020;38(5):925-928. doi:10.1016/j.ajem.2019.07.020, Iuliano AD, Brunkard JM, Boehmer TK, et al. During December 18, 2021, 22 U.S. states reported at least one COVID-19 case attributed to the Omicron variant. What is the Omicron Variant's Incubation Period and How Long Are You Of secondary cases, 90% had an incubation period of 6 days for Omicron and 7 days for Delta. Omicron is the dominant variant in the United States, making up about 59 percent of infections for the week ending Dec. 25, the Centers for Disease Control and Prevention said Tuesday. We enrolled COVID-19 infector/infectee pairs who lived within the Itako PHC jurisdiction and had a single definite close contact date with patients who had COVID-19 without other potential transmission settings. MMWR Morb Mortal Wkly Rep. Sep 10 2021;70(36):1255-1260. doi:10.15585/mmwr.mm7036e2, Siegel DA, Reses HE, Cool AJ, et al. Users guide to variant detection calculators. MMWR Morb Mortal Wkly Rep. Feb 4 2022;71(5):177-181. doi:10.15585/mmwr.mm7105e1, Olson SM, Newhams MM, Halasa NB, et al. The CDC says that its guidelines were updated to reflect growing evidence that suggests transmission of COVID-19 often occurs one to two days before the onset of symptoms and during the two to . doi:10.1016/S2213-2600(22)00011-X, Jayk Bernal A, Gomes da Silva MM, Musungaie DB, et al. A study released Tuesday by the CDC suggestes that the omicron variant may have a shorter incubation period 72 hours than previous variants of the disease, which typically took four days . according to reports from the CDC. The first patient infected with SARS-CoV-2 Omicron BA.5 was reported on July 4, 2022, to the Itako PHC in Ibaraki Prefecture, Japan. Sect. The best way to protect yourself and those around you is to get vaccinated, Oller said. Clin Infect Dis. How quickly do omicron symptoms appear? What's the incubation period? Health experts say incubation times could be changing due to omicron, but those who test early should continue testing even if they get negative results. Hoarse voice. This prioritization should be balanced with maintaining case investigation and contact tracing for outbreaks of confirmed cases of SARS-CoV-2 infection in high-risk congregate settings (e.g., long-term care facilities, correctional facilities, and homeless shelters) and for persons at increased risk for severe COVID-19related health outcomes. Although there is a shorter incubation period, you still need to test regularly if youve been exposed. Euro Surveill. One vaccinated patient was hospitalized for 2 days, and no deaths have been reported to date. MMWR Morb Mortal Wkly Rep. Jun 19 2020;69(24):759-765. doi:10.15585/mmwr.mm6924e2, Roxby AC, Greninger AL, Hatfield KM, et al. . Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2. Through this program, international air travelers are offered molecular testing of pooled samples collected upon arrival and a take-home collection kit (saliva collection for nucleic acid amplification test) to be used 35 days after arrival with subsequent sequencing of SARS-CoV-2positive specimens; persons in pools with a positive test result are contacted and advised to get retested using the home collection kit or another method. What is the incubation period of Omicron BA.2? Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Meta-analyses of studies published in 2020 identified a pooled mean incubation period of 6.5 days from exposure to symptom onset. Saving Lives, Protecting People, Itako Public Health Center of Ibaraki Prefectural Government, Ibaraki, Japan (T. Ogata), Public Health Center of Neyagawa City, Osaka, Japan (H. Tanaka), National Institute of Infectious Diseases. Am J Transplant. Dr. Edwards adds that it is too early to tell anything about the mortality rate and . In addition, CDC recommends that everyone aged 2 years wear masks in public indoor places in areas of substantial or high transmission. Clinical Microbiology and Infection. Delta's incubation period was about four days, . Jan 15 2021;doi:10.1001/jamainternmed.2020.9241, Matar R, Alrahmani L, Monzer N, et al. As a result of the more contagious BA.4 and BA.5 omicron subvariants, COVID-19's incubation period has changed in recent months, Chicago's top doctor previously revealed. doi:10.1136/bmj.n1098, Antonelli M, Pujol JC, Spector TD, Ourselin S, Steves CJ. 2022;6(5):294-302. doi:10.1016/s2352-4642(22)00027-x, Torjesen I. Covid-19: Omicron variant is linked to steep rise in hospital admissions of very young children. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Incubation periods can. Genomic evidence for reinfection with SARS-CoV-2: a case study. Pediatrics. CDC Updates and Shortens Recommended Isolation and Quarantine Period Feb 17 2022;386(7):698-700. doi:10.1056/NEJMc2119236, Leon TM, Dorabawila V, Nelson L, et al. mRNA Vaccine Effectiveness Against Coronavirus Disease 2019 Hospitalization Among Solid Organ Transplant Recipients. How long are. Characteristics and Disease Severity of US Children and Adolescents Diagnosed With COVID-19. During the past several years, CDC has intensified efforts to significantly expand genomic sequencing capacity at the federal and state levels. Classification of Omicron (B.1.1.529): SARS-CoV-2 variant of concern. Among 43 cases with initial follow-up, one hospitalization and no deaths were reported. A partially vaccinated person had received a COVID-19 vaccine but not completed the primary series 14 days before illness onset or receipt of a positive SARS-CoV-2 test result. Hospitalizations Associated with COVID-19 Among Children and Adolescents - COVID-NET, 14 States, March 1, 2020-August 14, 2021. Feb 10 2022;386(6):509-520. doi:10.1056/NEJMoa2116044, Sjoding MW, Dickson RP, Iwashyna TJ, Gay SE, Valley TS. Systematic review and meta-analysis of chest radiograph (CXR) findings in COVID-19. MMWR Morb Mortal Wkly Rep. Apr 8 2022;71(14):524-526. doi:10.15585/mmwr.mm7114a2, Slezak J, Bruxvoort K, Fischer H, Broder B, Ackerson B, Tartof S. Rate and severity of suspected SARS-Cov-2 reinfection in a cohort of PCR-positive COVID-19 patients. CDC: Study Finds A Shorter Incubation Period of 3 Days With Omicron, Compared to Delta. Mutations in Omicron might increase transmissibility, confer resistance to therapeutics, or partially escape infection- or vaccine-induced immunity. Jan 18 2022;327(3):281-283. doi:10.1001/jama.2021.23262, Nygaard U, Holm M, Hartling UB, et al. Among 43 cases with initial follow-up, one hospitalization and no deaths were reported. Omicron incubation period: How long until symptoms show? - Fast Company https://covid.cdc.gov/covid-data-tracker/#variant-proportions Top References CDC. Furthermore, children usually have mild symptoms, and average viral shedding might be less than that of an adult (15). J Ophthalmic Vis Res. Ogata T, Tanaka H. SARS-CoV-2 Incubation Period during the Omicron BA.5Dominant Period in Japan. (3,4) Presentation 2020/09/01/ 2020;98:180-186. doi:https://doi.org/10.1016/j.ijid.2020.06.052, Yang J, Zheng Y, Gou X, et al. This activity was reviewed by CDC and was conducted consistent with applicable federal law and CDC policy.. Comparison of Blood Counts and Markers of Inflammation and Coagulation in Patients With and Without COVID-19 Presenting to the Emergency Department in Seattle, WA. EClinicalMedicine. Is It Safe to Travel During the Holidays As the Omicron - Leisure SARS-CoV-2 B.1.1.529 (Omicron) Variant United States ** Based on CDC analysis of the sequences currently available, and accounting for clustering, CDC estimates a 95% chance of detecting the Omicron variant if it accounted for 0.03% of circulating SARS-CoV-2 lineages during the week ending November 13 and for 0.05% of circulating lineages during the week ending November 20 (4). Feb 2022;226(2):177-186. doi:10.1016/j.ajog.2021.08.054, Barbero P, Mugerza L, Herraiz I, et al. According to Japans Infectious Diseases Control Law, public health centers (PHCs) must be notified of all COVID-19 cases and conduct contact tracing (4). What's COVID's incubation period? Can Omicron spread if you're They help us to know which pages are the most and least popular and see how visitors move around the site. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. * SIG includes representatives from CDC, the National Institutes of Health (NIH), the Food and Drug Administration (FDA), the Biomedical Advanced Research and Development Authority (BARDA), the U.S. Department of Defense (DoD), the U.S. Department of Agriculture (USDA), and the U.S. Department of Health and Human Services (HHS). (1) A study conducted during high levels of Delta variant transmission reported an incubation period of 4.3 days,(2) and studies performed during high levels of Omicron variant transmission reported a median incubation period of 34 days.(3,4). doi:10.1136/bmj-2021-068632, Embi PJ, Levy ME, Naleway AL, et al. More information is available, Recommendations for Fully Vaccinated People, people who are up to date with their vaccines, Clinical Progression, Management, and Treatment, Alene M, Yismaw L, Assemie MA, Ketema DB, Gietaneh W, Birhan TY. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. The mean during the BA.1dominant period was 2.9 (95% CI 2.63.2) days, and the median was 2.7 (95% CI 2.53.0) days. Lancet. doi:10.1136/bmj.n385, Martin B, Dewitt PE, Russell S, et al. Symptoms can overlap with those of other viral respiratory illnesses. Get vaccinated, encourage those you love to get vaccinated and get boosted when it is recommended.. Uncommon presentations of COVID-19 can occur, might vary by the age of the patient, and are a challenge to recognize. Case investigations have identified exposures associated with international and domestic travel, large public events, and household transmission. Association between COVID-19 diagnosis and presenting chief complaint from New York City triage data. 2023;29(3):595-598. https://doi.org/10.3201/eid2903.221360. Chest. All HTML versions of MMWR articles are generated from final proofs through an automated process. Figure. The rapid emergence and worldwide detection of the SARS-CoV-2 Omicron variant underscores the importance of robust genomic surveillance systems and prompt information-sharing among global public health partners. Oct 1 2021;4(10):e2128568. For those without symptoms, CDC guidance states they are considered contagious at least two days before their positive test. When am I contagious if infected with omicron? - WTOP News Dermatology. Some data suggest the incubation period for Omicron may be closer to three days.. Some older adults can experience COVID-19 infection accompanied by delirium, falls, reduced mobility or generalized weakness, and glycemic changes. 2022/09/15 2022;doi:10.1007/s00431-022-04600-x, Zimmermann P, Pittet LF, Curtis N. How Common is Long COVID in Children and Adolescents? You will be subject to the destination website's privacy policy when you follow the link. For purposes of entry into the United States, vaccines accepted will include FDA approved or authorized and WHO Emergency Use Listing vaccines. High rates of rapid antigen test positivity after 5 days of isolation for COVID-19. The most recent information: Along with its increased transmissibility and potentially milder symptoms, Omicron may also have a shorter incubation period than Delta and other strains. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Lancet Reg Health Eur. The risk of severe COVID-19 increases with increasing age over 40 years and with increasing number of certain, Shortness of breath or difficulty breathing. American Journal of Clinical Pathology. Investigation of a SARS-CoV-2 B.1.1.529 (Omicron) Variant Cluster - Nebraska, November-December 2021. For the most recent updates on COVID-19, visit our coronavirus news page. BMJ. 2022/02/01/ 2022;13:100278. doi:https://doi.org/10.1016/j.lanepe.2021.100278, Jansen L, Tegomoh B, Lange K, et al. Epidemiology of Infections with SARS-CoV-2 Omicron BA.2 Variant, Hong Kong, January-March 2022. In September 2021, a systematic review of all MIS-A publications reported a total of 221 cases, with a median age of 21 years and 70% of the cases being male. Hospitalization of Infants and Children Aged 0-4 Years with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 2020-February 2022. CDC twenty four seven. Coronavirus Incubation Period: How Long and When Most Contagious - WebMD 2020/06/01/ 2020;7(6):e438-e440. What We Know About Omicron BA.4 and BA.5 - Verywell Health Risk of clinical sequelae after the acute phase of SARS-CoV-2 infection: retrospective cohort study. Jul 1 2021;18:E66. MMWR Morb Mortal Wkly Rep. Aug 13 2021;70(32):1081-1083. doi:10.15585/mmwr.mm7032e1, National Center for Immunization and Respiratory Diseases (NCIRD), Post-COVID Conditions: Healthcare Providers, Decontamination & Reuse of N95 Respirators, Purchasing N95 Respirators from Another Country, Powered Air Purifying Respirators (PAPRs), U.S. Department of Health & Human Services. Fatigue. Even though the incubation period did not statistically differ, serial interval was significantly decreased in Omicron (mean 4.8 vs. 5.3, median 4 vs. 5) and was again more grouped to the left (IQR 3 vs. 5). A shorter incubation suggests a shorter quarantine period for BA.5 than for other variants. Coronavirus Disease 2019 Case Surveillance - United States, January 22-May 30, 2020. Omicron's Incubation Period Is Short: Here's Why That - Yahoo Finance Underlying Medical Conditions Associated With Severe COVID-19 Illness Among Children. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. The mean virus incubation period during the SARS-CoV-2 Omicron BA.5dominant period in Japan was 2.6 (95% CI 2.52.8) days, which was less than during the Delta-dominant period. Omicron incubation: Can COVID variant get you sick quicker? - Miami Herald Emerg Infect Dis. Genomic sequencing showed that 92% of 22,953 variants of concern sampled in Japan during January 3February 6 were BA.1 (9). SARS-CoV-2 in pregnancy: characteristics and outcomes of hospitalized and non-hospitalized women due to COVID-19. . Journal of investigative medicine : the official publication of the American Federation for Clinical Research. CDC COVID-19 Response Team. May 2020;94:91-95. doi:10.1016/j.ijid.2020.03.017, Tenforde MW, Billig Rose E, Lindsell CJ, et al. Carla M. Delgado is a health and culture writer based in the Philippines. Clin Infect Dis. These cookies may also be used for advertising purposes by these third parties. Table 2. Because symptoms may progress quickly, close follow-up is needed, especially for older adults, people with disabilities, people with immunocompromising conditions, and people with medical conditions that place them at greater risk for severe illness or death. 552a; 44 U.S.C. the date of publication. Views equals page views plus PDF downloads. Overall, the average incubation period of all the variants was 6.57 days, ranging from 1.8 to 18.87 days. 3501 et seq. The median incubation period was 2-5 days (based on earliest and latest exposure). URL addresses listed in MMWR were current as of A vaccinated person had completed the primary series of a Food and Drug Administrationauthorized or approved COVID-19 vaccine 14 days before illness onset or receipt of a positive SARS-CoV-2 test result. There are arguments that could be made both towards shortening or lengthening, Weiss said. Overall, 21 (91%) of 23 interviewed attendees participated in the convention all 3 days. All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Reinfection Rates Among Patients Who Previously Tested Positive for Coronavirus Disease 2019: A Retrospective Cohort Study. doi:10.1016/S2214-109X(21)00593-3, Belay ED, Abrams J, Oster ME, et al. Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults: A Systematic Review. Mar 2022;28(3):756-759. doi:10.3201/eid2803.212607, Stokes EK, Zambrano LD, Anderson KN, et al. Thank you for taking the time to confirm your preferences. BMJ. We take your privacy seriously. Sep 18 2020;doi:10.1093/cid/ciaa1419, Wortham JM, Lee JT, Althomsons S, et al. Table 1 - SARS-CoV-2 Incubation Period during the Omicron BA.5-Dominant We must remember, however, that this is an average, and some people may have symptoms as early as two days or as late as 14 days after exposure.. Sep 13 2022;226(5):797-807. doi:10.1093/infdis/jiac118, Parker EPK, Desai S, Marti M, et al. The Journal of infection. days (95% CI). Read our. and/or the original MMWR paper copy for printable versions of official text, figures, and tables. Thank you, {{form.email}}, for signing up. Third, exposures from sources other than the infector of the pair might have been missed. Comment submitted successfully, thank you for your feedback. Characteristics, Outcomes, and Severity Risk Factors Associated With SARS-CoV-2 Infection Among Children in the US National COVID Cohort Collaborative. 2021;156(2):185-197. doi:10.1093/ajcp/aqab052, Levi M, Thachil J, Iba T, Levy JH. This is shorter than with Delta and earlier variants. Volume 28, Number 4April 2022 - Emerging Infectious Diseases journal CDC recommends prioritizing case investigation and contact tracing for confirmed COVID-19 cases attributed to the Omicron variant. Data from December 2021 suggests that Omicron's average incubation period is around two to four days, which would mean that symptoms may develop faster after exposure compared to other variants. Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women - a systematic review and meta-analysis. MMWR Morb Mortal Wkly Rep. Apr 30 2021;70(17):644-650. doi:10.15585/mmwr.mm7017e3, Chevinsky JR, Tao G, Lavery AM, et al. Finally, increasing patient numbers might have influenced the quality of contact tracing by the PHC. Fifth, the variant type was not confirmed by using genomic sequencing. The first U.S. case of COVID-19 attributed to the Omicron variant was detected on December 1, 2021. N Engl J Med. A recent study from the Centers for Disease Control and Prevention (CDC) analyzed data from six people who contracted the Omicron variant of SARS-CoV-2, the virus that causes COVID-19, and found that 73 hours (or three days) was the typical incubation period for patients. Among these cases of COVID-19 attributed to the Omicron variant, 34 (79%) occurred inpersons whocompleted the primary series of an FDA-authorized or approved COVID-19 vaccine 14 days before symptom onset or receipt of a positive SARS-CoV-2 test result, including 14 who had received an additional or booster dose; five of the 14 persons had received the additional dose <14 days before symptom onset.
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